Yes, in addition to fleas, Frontline also kills ticks and mange mites. The insecticide used in Frontline is broad-spectrum and kills many different types of parasites before they are able to lay eggs and reproduce.
It is recommended that you give your cat or dog Frontline for several successive months in order to treat mange mites, so that the entire population including immature in juvenile mites can be killed as they become adults.
You can also apply a topical hydrocortisone cream in order to reduce the itching from the mange, as long as the skin is not broken. If there are any open sores, your veterinarian may prescribe an antibiotic in order to prevent or treat any bacterial skin infections